Xiangwei (Shaun) Du, PhD

Assistant Clinical Professor
(Chemistry/Toxicology)

  • BS: Shaanxi Normal University, Xi’an, China
  • PhD: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China
  • Postdoctoral Fellowship: Iowa State University, Ames, IA
Xiangwei (Shaun) Du

Office: D202 Veterinary Medical Diagnostic Laboratory
Laboratory: D205 Veterinary Medical Diagnostic Laboratory
Phone: (573) 884-9240
Email:  x.du@missouri.edu

RESEARCH INTERESTS

My research focuses on analytical toxicology and organic synthesis. For toxicology, I work on developing new analytical assays to detect toxins, nutrition, and veterinary drugs as well as isolation, purification, and characterization of their new metabolites. For organic synthesis, I am interested in designing new probes for biosensor and new veterinary drugs.

Current major interests have centered on fungal metabolites (mycotoxins), tall fescue alkaloids, phyto and fungal estrogens, and nutrition (vitamins).

  • Mycotoxins:
    • Mycotoxin culture production (aflatoxin, zearalenone, ochratoxin A, fumonisin, T-2 toxin, etc) in large quantities for animal feeding studies.
    • In vitro and in vivo examination of binders for decontaminating of animal feeds containing high levels of mycotoxins.
    • Developing rapid methods for the quantification of mycotoxins by LC-MS/MS in various matrices.
    • Identify new mycotoxin metabolites.
  • Fescue alkaloids:
    • Developing rapid methods for the quantification of fescue alkaloids by LC-MS/MS.
    • Identify new alkaloid metabolites.
  • Nutrition:
    • Developing rapid methods for the quantification of vitamin A, vitamin E, vitamin K, and vitamin D.

SELECTED PUBLICATIONS

Publications

Since joining the University of Missouri

  • Zeltwanger, J. M.; Bailey, E. A.; Hergenreder, J.; Canterbury, L.; Brake, D.; Petzel, E.; Nelson, B.; Du, X.; Evans, T. “The Ability of an Enhanced Zeolite-Based Flow Agent to Mitigate the Effects of Ergot-Like Alkaloids Consumed by Beef Cattle”, J. Anim. Sci., 2022, 100, 176-177.
  • Yan, Q.; Nosratabad, N. A.; Du, X.; Ketelboeter, T.; Wan, C.; Cai Z. “Highly effective lead removal by novel alkaline biochar prepared by pyrolysis of woody biomass impregnated with low-level NaOH”, J. Hazard. Mater. Adv. 2025, 18, 100657. 
  • Kerr, N. R.; Mossman, C. W.; Chou, C. H.; Bunten, J. M.; Kelty, T. J.; Childs, T. R.; Rector, R. S.; Arnold, W. D.; Grisanti, L. A.; Du, X.; Booth, F. W. “Hindlimb immobilization induces insulin resistance and elevates mitochondrial ROS production in the hippocampus of female rats”, J. Appl. Physiol. 2024, 137, 512-526. 
  • Nava-Ramirez, M. J.; Maguey-Gonzalez, J. A.; Gomez-Rosales, S.; Hernandez-Ramirez J. O.; Latorre, J. D.; Du, X.; Lopez-Coello, C.; Hargis, B. M.; Tellez-Isaias, G.; Vazquez-Duran, A.; Mendez-Albores, A. “Efficacy of powdered alfalfa leaves to ameliorate the toxic effects of aflatoxin B1 in turkey poults”, Mycotoxin Res. 2024, 40, 269-277. 
  • Bailey, E. A.; Adams, M. J.; Meng, K. R.; Zeltwanger, J. M.; Brake, D. W.; Du, X. “Interaction of an herbicide containing aminopyralid and metsulfuron and nitrogen fertilizer in tall fescue pastures grazed by stocker cattle”, App. Anim. Sci., 2024, 40, 103-111.
  • Du, X.; Schrunk, D. E.; Imerman, P. M.; Tahara, J.; Tkachenko, A.; Guag, J.; Reimschuessel R.; Rumbeiha, W. K. “Extensive Evaluation of a Method for Quantitative Measurement of Aflatoxins B1 and M1 in Animal Urine Using High-Performance Liquid Chromatography with Fluorescence Detection”, J. AOAC Int. 2023, 106, 645-651.
  • Maguey-Gonzalez, J. A.; Nava-Ramirez, M. J.; Gomez-Rosales, S.; Angeles, M. L.; Solis-Cruz, B.; Du, X.; Hargis, B. M.; Tellez-Isaias, G. “Evaluation of the efficacy of humic acids to counteract the toxic effects of aflatoxin B1 in turkey poults”, Front. Vet. Sci. 2023, 10, 1-11. 
  • Deng, Z; Jang, K. B.; Jalukar, S; Du, X.; Kim, S. W. “Efficacy of Feed Additive Containing Bentonite and Enzymatically Hydrolyzed Yeast on Intestinal Health and Growth of Newly Weaned Pigs under Chronic Dietary Challenges of Fumonisin and Aflatoxin”, Toxins. 2023, 15, 433.
  • Sun, Y.; Li, Q.; Du, X.; Thipe, V.; Vardhanabhuti, B.; Senguptu, S.; Katti, K.; Wan, C. “Lignin-containing Nanocellulose for in situ Chemical-Free Synthesis of AgAu-based Nanoparticles with Potent Antibacterial Activities”, ACS Omega, 2022, 7, 41548-41558.
  • Bailey, E. A.; Meng K. R.; Brake, D. W.; Du, X.; Zeltwanger, J. M. “Prescribed burning of endophyte-infected tall fescue plots: Effects on forage production, ergot-like alkaloid concentrations, and botanical composition”, App. Anim. Sci., 2022, 38, 551-559.