Etiology: PVM is an enveloped RNA paramyxovirus of the pneumovirus group.
Incidence: The incidence of disease in research colonies is rare for PVM.
Transmission: The primary route of infection is by direct contact with infected animals during the first two weeks of infection when the virus is shed. The disease is usually enzootic in a colony in which susceptible animals are regularly introduced. Interspecies transmission (to and from gerbils, mice, hamsters) is possible.
Clinical Signs: PVM infections usually produce no clinical disease.
Pathology: Histologic lesions may include very mild perivascular and focal interstitial lymphocytic infiltrates.
Diagnosis: Most respiratory virus infections are identified by screening sera by MFI or IFA.