Etiology: Pseudomonas aeruginosa is a Gram-negative motile rod.
Incidence: The incidence of infection with Pseudomonas aeruginosa is low.
Transmission: Pseudomonas can colonize the intestinal tract of mice following consumption of nonsterile water.
Clinical signs: There are no clinical signs in immunocompetent mice and most immunocompromised mice. There have been a few instances in severely immunocompromised mice in which clinical inner ear disease has been attributed to natural P. aeruginosa infection where animals were seen “circling” or “rolling.”
Pathology: A septicemic and endotoxemic syndrome has been reported in colonized mice that have been treated with immunosuppressive drugs or X-irradiation.
Diagnosis: P. aeruginosa can be diagnosed by culture.