Buphthalmia (congenital glaucoma)

Etiology:  Congenital glaucoma caused by an autosomal recessive defect with incomplete penetrance.  There is an absence or underdevelopment of the outflow channels with incomplete cleavage of the iridocorneal angles.

Incidence:  The incidence of bupthalmia is moderate, and most commonly occurs in New Zealand White rabbits [2].

Clinical Signs:  Clinical signs may occur as early as 2 to 3 weeks of age, but are more common at 3 to 4 months of age.  Signs include slight cloudiness progressing to increasing cloudiness of the cornea, a prominent eyeball (arrow), conjunctivitis, keratitis, ulceration, and rupture of the cornea.  The condition may be unilateral or bilateral.

Diagnosis:  Diagnosis is made by performing a physical examination.

Buphthalmia (congenital glaucoma)

2.            The Laboratory Rabbit, Guinea Pig, Hamster, And Other Rodents. 1 ed2012, 225 Wyman Street, Waltham, MA 02451: Elsevier.