Lyndon M. Coghill, PhD

Assistant Research Professor

Director of Informatics

  • B.S., Western Illinois University
  • Ph.D., University of New Orleans
  • Postdoctoral Fellowship, Field Museum of Natural History, Chicago
  • Postdoctoral Fellowship, Louisiana State University
Lyndon M. Coghill

Building Address: 106 Bond Life Sciences Center
Phone Number: 573-882-3026
Email: lcoghill@missouri.edu
Lab Website: https://bioinformatics.missouri.edu/

RESEARCH INTERESTS

Dr. Coghill’s research focuses on developing and using modern data science methods and tools (bioinformatics, machine learning, and more) to help understand molecular evolution and adaptation in response to extreme environments (caves, climate, nonnative species etc.) and conditions (zoonotic and infectious disease, host-parasite interactions).

SELECTED PUBLICATIONS

  1. Marino ME, Mironovich MA, Ineck NE, Citino SB, Emerson JA, Maggs DJ, Coghill LM, Dubovi EJ, Turner RC, Carter RT, Lewin AC. Full Viral Genome Sequencing and Phylogenomic Analysis of Feline Herpesvirus Type 1 (FHV-1) in Cheetahs (Acinonyx jubatus). Viruses. 2021 Nov 19;13(11). doi: 10.3390/v13112307. PubMed PMID: 34835113; PubMed Central PMCID: PMC8625435.
  2. Khalyfa A, Qiao Z, Raju M, Shyu CR, Coghill L, Ericsson A, Gozal D. Monocarboxylate Transporter-2 Expression Restricts Tumor Growth in a Murine Model of Lung Cancer: A Multi-Omic Analysis. Int J Mol Sci. 2021 Sep 30;22(19). doi: 10.3390/ijms221910616. PubMed PMID: 34638954; PubMed Central PMCID: PMC8508890.
  3. Calderon R, Jeong C, Ku H, Coghill L, Ju Y, Kim N, Ham J. Changes in the Microbial Community in Soybean Plots Treated with Biochar and Poultry Litter. Agronomy. 2021 July; 11(7):1428. doi: 10.3390/agronomy11071428.
  4. Lewin AC, Coghill LM, Mironovich M, Liu CC, Carter RT, Ledbetter EC. Phylogenomic Analysis of Global Isolates of Canid Alphaherpesvirus 1. Viruses. 2020 Dec 10;12(12). doi: 10.3390/v12121421. PubMed PMID: 33322040; PubMed Central PMCID: PMC7764265.
  5. Cohen A, Cox C, Masucci M, Le T, Cowan T, Coghill L, Holmlund T, Elvevåg B. Digital Phenotyping Using Multimodal Data. Current Behavioral Neuroscience Reports. 2020 September; 7:212-220. doi: 10.1007/s40473-020-00215-4.
  6. Lewin AC, Coghill LM, McLellan GJ, Bentley E, Kousoulas KG. Genomic analysis for virulence determinants in feline herpesvirus type-1 isolates. Virus Genes. 2020 Feb;56(1):49-57. doi: 10.1007/s11262-019-01718-3. Epub 2019 Nov 27. PubMed PMID: 31776852; PubMed Central PMCID: PMC7027352.
  7. Thaljeh LF, Rothschild JA, Naderi M, Coghill LM, Brown JM, Brylinski M. Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs. Biomolecules. 2019 Oct 12;9(10). doi: 10.3390/biom9100603. PubMed PMID: 31614784; PubMed Central PMCID: PMC6843332.
  8. Rider PJF, Coghill LM, Naderi M, Brown JM, Brylinski M, Kousoulas KG. Identification and Visualization of Functionally Important Domains and Residues in Herpes Simplex Virus Glycoprotein K(gK) Using a Combination of Phylogenetics and Protein Modeling. Sci Rep. 2019 Oct 10;9(1):14625. doi: 10.1038/s41598-019-50490-9. PubMed PMID: 31601827; PubMed Central PMCID: PMC6787236.
  9. Höhna S, Coghill LM, Mount GG, Thomson RC, Brown JM. P3: Phylogenetic Posterior Prediction in RevBayes. Mol Biol Evol. 2018 Apr 1;35(4):1028-1034. doi: 10.1093/molbev/msx286. PubMed PMID: 29136211.
  10. Fujimoto K, Coghill LM, Weier CA, Hwang LY, Kim JY, Schneider JA, Metzker ML, Brown JM. Short Communication: Lack of Support for Socially Connected HIV-1 Transmission Among Young Adult Black Men Who Have Sex with Men. AIDS Res Hum Retroviruses. 2017 Sep;33(9):935-940. doi: 10.1089/AID.2016.0228. Epub 2017 Apr 18. PubMed PMID: 28398775; PubMed Central PMCID: PMC5576226.
  11. Hinchliff CE, Smith SA, Allman JF, Burleigh JG, Chaudhary R, Coghill LM, Crandall KA, Deng J, Drew BT, Gazis R, Gude K, Hibbett DS, Katz LA, Laughinghouse HD 4th, McTavish EJ, Midford PE, Owen CL, Ree RH, Rees JA, Soltis DE, Williams T, Cranston KA. Synthesis of phylogeny and taxonomy into a comprehensive tree of life. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12764-9. doi: 10.1073/pnas.1423041112. Epub 2015 Sep 18. PubMed PMID: 26385966; PubMed Central PMCID: PMC4611642.
  12. Coghill LM, Darrin Hulsey C, Chaves-Campos J, García de Leon FJ, Johnson SG. Next generation phylogeography of cave and surface Astyanax mexicanus. Mol Phylogenet Evol. 2014 Oct;79:368-74. doi: 10.1016/j.ympev.2014.06.029. Epub 2014 Jul 8. PubMed PMID: 25014568.
  13. Lorenz OT, Smith P, Coghill LM. Condition and morphometric changes in tilapia (Oreochromis sp.) after an eradication attempt in Southern Louisiana. Neobiota. 2014 January; 20:49-59. doi: 10.3897/neobiota.20.5062.
  14. Coghill LM, Hulsey CD, Chaves-Campos J, García de Leon FJ, Johnson SG. Phylogeography and conservation genetics of a distinct lineage of sunfish in the Cuatro Ciénegas valley of Mexico. PLoS One. 2013;8(10):e77013. doi: 10.1371/journal.pone.0077013. eCollection 2013. PubMed PMID: 24130826; PubMed Central PMCID: PMC3794925.
  15. Chaves-Campos J, Coghill LM, García de León FJ, Johnson SG. The effect of aquatic plant abundance on shell crushing resistance in a freshwater snail. PLoS One. 2012;7(9):e44374. doi: 10.1371/journal.pone.0044374. Epub 2012 Sep 6. PubMed PMID: 22970206; PubMed Central PMCID: PMC3435308.
  16. Chaves-Campos J, Coghill L, Al-Salamah M, DeWitt T, Johnson S. Field heritabilities and lack of correlation of snail shell form and anti-predator function estimated using Bayesian and maximum likelihood methods. Evolutionary Ecology Research. 2012; 14:743–755.