Associate Professor

• PhD, Kansas State University
• DVM, University of Minnesota

Email: JohnsonGS@missouri.edu

TEACHING

Veterinary Genomics

RESEARCH INTERESTS

Whole genome sequencing to identify the molecular genetic causes of heritable canine diseases

SELECTED PUBLICATIONS (from 126 total)

Jaffey JA, Bullock G, Guo J, Mhlanga-Mutangadura T, O’Brien DP, Coates JR, Morrissey R, Hutchison R, Donnelly KS, Cohn LA, Katz ML, Johnson GS. Novel Homozygous  ADAMTS2  Variants and Associated Disease Phenotypes in Dogs with Dermatosparactic Ehlers-Danlos Syndrome. Genes (Basel). 2022 Nov 19;13(11):2158. doi: 10.3390/genes13112158. PMID: 36421833; PMCID: PMC9690363.

Bullock G, Johnson GS, Mhlanga-Mutangadura T, Petesch SC, Thompson S, Goebbels S, Katz ML. Lysosomal storage disease associated with a CNP sequence variant in Dalmatian dogs. Gene. 2022 Jul 1;830:146513. doi: 10.1016/j.gene.2022.146513. Epub 2022 Apr 18. PMID: 35447247.

Whitacre LK, Wildhaber ML, Johnson GS, Durbin HJ, Rowan TN, Tribe P, Schnabel RD, Mhlanga-Mutangadura T, Tabor VM, Fenner D, Decker JE. Exploring genetic variation and population structure in a threatened species, Noturus placidus, with whole-genome sequence data. G3 (Bethesda). 2022 Apr 4;12(4):jkac046. doi: 10.1093/g3journal/jkac046. PMID: 35188205; PMCID: PMC8982419.

St Jean SC, Jortner BS, Doan RN, Dindot SV, Johnson GS, Bullock G, Whitley DB, Levine JM, Hancock SK, Ambrus A, Porter BF. Pathologic characterization of canine multiple system degeneration in the Ibizan hound. Vet Pathol. 2022 Jan;59(1):132-137. doi: 10.1177/03009858211043088. Epub 2021 Sep 7. PMID: 34490804.

Leach SB, Briggs M, Hansen L, Johnson GS. Prevalence, geographic distribution, and impact on lifespan of a dilated cardiomyopathy-associated RNA-binding motif protein 20 variant in genotyped dogs. J Vet Cardiol. 2022 Apr;40:119-125. doi: 10.1016/j.jvc.2021.05.002. Epub 2021 May 21. PMID: 34144877.

Edwards RJ, Field MA, Ferguson JM, Dudchenko O, Keilwagen J, Rosen BD, Johnson GS, Rice ES, Hillier D, Hammond JM, Towarnicki SG, Omer A, Khan R, Skvortsova K, Bogdanovic O, Zammit RA, Aiden EL, Warren WC, Ballard JWO. Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome. BMC Genomics. 2021 Mar 16;22(1):188. doi: 10.1186/s12864-021-07493-6. PMID: 33726677; PMCID: PMC7962210.

Jaffey JA, Reading NS, Abdulmalik O, Kreisler R, Bullock G, Wiest A, Villani NA, Mhlanga-Mutangadura T, Johnson GS, Cohn LA, Isaza N, Harvey JW, Giger U. Clinical, metabolic, and molecular genetic characterization of hereditary methemoglobinemia caused by cytochrome b 5  reductase deficiency in 30 dogs. Sci Rep. 2020 Dec 8;10(1):21399. doi: 10.1038/s41598-020-78391-2. PMID: 33293645; PMCID: PMC7723051.

Letko A, Minor KM, Friedenberg SG, Shelton GD, Salvador JP, Mandigers PJJ, Leegwater PAJ, Winkler PA, Petersen-Jones SM, Stanley BJ, Ekenstedt KJ, Johnson GS, Hansen L, Jagannathan V, Mickelson JR, Drögemüller C. A  CNTNAP1  Missense Variant Is Associated with Canine Laryngeal Paralysis and Polyneuropathy. Genes (Basel). 2020 Nov 27;11(12):1426. doi: 10.3390/genes11121426. PMID: 33261176; PMCID: PMC7761076.

Yu Y, Hasegawa D, Chambers JK, Kojima K, Asada R, Johnson GS, Uchida K. Magnetic Resonance Imaging and Histopathologic Findings From a Standard Poodle With Neonatal Encephalopathy With Seizures. Front Vet Sci. 2020 Nov 10;7:578936. doi: 10.3389/fvets.2020.578936. PMID: 33244473; PMCID: PMC7683776.

Abrams SR, Hawks AL, Evans JM, Famula TR, Mahaffey M, Johnson GS, Mason JM, Clark LA. Variants in  FtsJ RNA 2′-O-Methyltransferase 3  and Growth Hormone 1 are associated with small body size and a dental anomaly in dogs. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24929-24935. doi: 10.1073/pnas.2009500117. Epub 2020 Sep 21. PMID: 32958658; PMCID: PMC7547249.

Guo J, Johnson GS, Cook J, Harris OK, Mhlanga-Mutangadura T, Schnabel RD, Jensen CA, Katz ML. Neuronal ceroid lipofuscinosis in a German Shorthaired Pointer associated with a previously reported  CLN8  nonsense variant. Mol Genet Metab Rep. 2019 Oct 21;21:100521. doi: 10.1016/j.ymgmr.2019.100521. PMID: 31687336; PMCID: PMC6819867.

Jaffey JA, Bullock G, Teplin E, Guo J, Villani NA, Mhlanga-Mutangadura T, Schnabel RD, Cohn LA, Johnson GS. A homozygous ADAMTS2 nonsense mutation in a Doberman Pinscher dog with Ehlers Danlos syndrome and extreme skin fragility. Anim Genet. 2019 Oct;50(5):543-545. doi: 10.1111/age.12825. Epub 2019 Jul 11. PMID: 31294848; PMCID: PMC6771693.

Villani NA, Bullock G, Michaels JR, Yamato O, O’Brien DP, Mhlanga-Mutangadura T, Johnson GS, Katz ML. A mixed breed dog with neuronal ceroid lipofuscinosis is homozygous for a CLN5 nonsense mutation previously identified in Border Collies and Australian Cattle Dogs. Mol Genet Metab. 2019 May;127(1):107-115. doi: 10.1016/j.ymgme.2019.04.003. Epub 2019 Apr 17. PMID: 31101435; PMCID: PMC6555421.